Quinoped Cream

1. Name Of The Medicinal Product

QUINOPED™ CREAM

2. Qualitative And Quantitative Composition

Benzoyl Peroxide BP	5.0%
Potassium Hydroxyquinoline Sulphate BP	0.5%

3. Pharmaceutical Form

Quinoped Cream is a cream-coloured astringent cream.

4. Clinical Particulars

4.1 Therapeutic Indications

Quinoped Cream is indicated in the treatment of tinea pedis (athlete's foot) and other related fungal infections.

4.2 Posology And Method Of Administration

Route of administration: For topical use only.

Adults, children and the elderly: Spread thinly over all the affected area and gently massage until no trace of the cream can be seen on the skin surface. Apply morning and night.

4.3 Contraindications

Known sensitivity to either of the active ingredients. Quinoped Cream is for topical use only.

4.4 Special Warnings And Precautions For Use

Care should be taken to avoid contact with dyed fabrics as this preparation may adversely affect dye fastness. In a few isolated cases overreaction to Quinoped Cream may occur. To avoid this possibility select a small area of skin on the feet, apply the cream and leave for twelve hours. If severe irritation or pronounced redness occurs do not proceed.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

Benzoyl Peroxide is an oxidising agent. Hence Quinoped Cream should not be used at the same time as other topical agents which would react with an oxidising agent.

4.6 Pregnancy And Lactation

Quinoped Cream is not contra-indicated in pregnancy or lactation.

4.7 Effects on ability to drive and use machine

Not applicable.

4.8 Undesirable Effects

Not applicable.

4.9 Overdose

Not applicable.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

Benzoyl Peroxide functions as a keratolytic and facilitates the removal of macerated tissue and associated debris. Potassium Hydroxyquinoline Sulphate has anti-fungal and deodorant properties. In addition Quinoped Cream is formulated in an astringent cream base which helps dry the infected toe clefts.

5.2 Pharmacokinetic Properties

Not applicable. Quinoped Cream is for topical use only.

5.3 Preclinical Safety Data

None stated.

6. Pharmaceutical Particulars

6.1 List Of Excipients

Lactic Acid BP, White Soft Paraffin BP, Edetic Acid BP, Sodium Acid Phosphate BP, Maize Starch BP, cetyl stearyl alcohol, sodium cetyl stearyl sulphate, PEG 40 castor oil, Purified Water BP.

6.2 Incompatibilities

Not applicable.

6.3 Shelf Life

Three years.

6.4 Special Precautions For Storage

Quinoped Cream should be stored in a cool dry place avoiding extremes of temperature i.e. not less than 5°C and not more than 30°C.

6.5 Nature And Contents Of Container

Quinoped Cream is available in low density polyethylene tubes with flush fitting cap containing 25 g of product.

6.6 Special Precautions For Disposal And Other Handling

No special instructions.

8. Marketing Authorisation Number(S)

PL 0291/0002

10. Date Of Revision Of The Text

January 1998

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